Clonidine Premedication Decreases Propofol Consumption During Bispectral Index® (BIS®) Monitored Propofol-Ketamine Technique for Office-based Surgery

Written By: Barry L. Friedberg, MD and Jeffrey C. Sigl, PhD
Date Published: Mon, 2000-05-01

Propofol-ketamine anesthesia is a room air, spontaneous ventilation (RASV), dissociative intravenous (IV) sedation technique reported to have a near-zero postoperative nausea and vomiting (PONV) rate. Clonidine premedication has been reported to control blood pressure intra- and postoperatively, as well as to reduce the requirements for hypnotic agents. The Bispectral Index® (BIS®) monitor is a reproducible, objective, observer independence, quantitative measurement of the hypnotic state.